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Title   한국인 악성 림프종의 임상상 ( Malignant Lymphomas in Korea )
Publicationinfo   1992 Jan; 024(01): 92-102.
Key_word   Malignant lymphoma, Korea
Full-Text  
Abstract   It has been known that there are considerable geographic and ethnic differences in the inci- dence, age distribution, and histologic subtypes of lymphoma. We studied the clinical characteristics of 500 patients with malignant lymphomas newly di- agnosed at Seoul National University Hospital from Jan. 1978 to Dec. 1987. Hodgkins disease was uncommon and accounted for 11.4% of all lymphomas. The most common type of non-Hodgkins lymphomas was diffuse histiocytic lymphoma of Rappaport(54.6%) and nodular lymphoma was very rare(4.5%). In Hodgkins disease, mixed cellularity type was most common(49.1%) and nodular sclerosis type was rare(8.8%). High proportion of lymphomas(about 1/2 of all lymphomas) were originated from the extranodal sites. Among non-Hodgkin's lymphomas, we observed the difference in survival duration between low grade and intermediate grade group(p<0.05). According to multivariate analysis using Cox regression hazard mode, stage and liver in- volvement were the most useful prognostic factors predicting survival in diffuse histiocytic lymphoma patients. In conclusion, the characteristics of malignant lymphomas in Korea differ from those in the western countries but are similar to those in China and Japan.
저 자   김흥태(Heung Tae Kim),임영혁(Young Hyuk Im),서창인(Chang In Suh),박영석(Young Suk Park),강원기(Won Ki Kang),허대석(Dae Seog Heo),방영주(Yung Jue Bang),박선양(Seon Yang Park),김병국(Byoung Kook Kim),김노경(Noe Kyeong Kim)